• Australia has one of the highest cannabis prevalence rates in the world and socio-political discussions rage about the legalisation of cannabis for medical and scientific purposes.

    The cannabis plant typically used recreationally consists of a number of cannabinoids (e.g. delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD)) that are present in different ratios, and may have differing effects on brain, general mental health, and wellbeing, in regular long-term cannabis smokers. Emerging evidence suggests that cannabidiol (CBD) may have neuroprotective properties and potentially offset the adverse effects of prolonged cannabis smoking. However, there is a lack of evidence regarding whether modifying the relative ratio of cannabinoids in smoked cannabis can alter brain effects. The current gaps in knowledge raise significant ethical issues for health care providers seeking evidence-based recommendations.

    This study will be the first naturalistic human examination of the links between prolonged exposure to various compounds within cannabis, brain health, and associated cognitive and psychological factors.

    This study is currently recruiting participants from the Northern Rivers region of NSW. We are recruiting two groups of participants – (1) regular cannabis smokers, and (2) non-using controls.

    To participate, follow this link.

    For any questions, feel free to contact our research team at:

    Phone: 0414 202 371

    Email: cannabis.study@monash.edu

    This study has been approved by the Monash University Human Research Ethics Committee (MUHREC): Project Number: 13390